Research-driven chemistry partner supporting pharmaceutical, nutraceutical, biotech, agrochemical and specialty chemical organizations from milligram discovery projects to kilogram-scale development.
We focus on uncompromising quality standards, cost-effective solutions, transparent communication and delivery timelines that help partners move faster in discovery and development.
Sygmoid Chemical Sciences Pvt. Ltd. is a Hyderabad-based chemical synthesis company with capabilities in discovery chemistry, custom synthesis, development and manufacturing support. The team designs concise and robust synthetic routes for new chemical entities, advanced intermediates, impurities, key starting materials, fine chemicals, nutraceutical-relevant molecules, fluorescent dyes and agrochemical intermediates.
Our work culture emphasizes confidentiality, innovation, price competitiveness, information transparency and reliable timelines.

From literature search and route scouting to process optimization and analytical support.
NCE design support, heterocyclic scaffolds, SAR-oriented analog synthesis and small focused libraries.
Exclusive synthesis of target molecules, rare intermediates, building blocks, impurities and reference standards.
Route refinement, scale-up support, purification strategy, impurity control and campaign-based supply.
Experienced scientific leadership with strong academic, industrial and international collaboration background.

Medicinal, organic and nutraceutical chemist; Chief Scientist (Superannuated), CSIR-IICT, Hyderabad. 40+ years of experience in medicinal chemistry, heterocyclic chemistry and organic synthesis, with involvement in about 20 international and national collaborative projects, including collaborations with GSK, DuPont, Arqule, Evolva, FMC, RGCB Trivandrum and Ranbaxy. His profile includes research publications, patents, Ph.D. guidance, postgraduate mentoring and AI-enabled drug discovery knowledge.

Synthetic R&D chemist with 14+ years of academic and industrial experience. Ph.D. from CSIR-IICT and postdoctoral research at Chungnam National University, Republic of Korea. Expertise includes heterocycles, API intermediates, impurities, fine chemicals, fluorescent dyes, contract research, custom synthesis and process development.
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R&D and pilot-scale infrastructure with analytical access to support confident project delivery.

Fume hoods, rotary evaporators, chiller, high-vacuum and high-temperature distillation, pressure filtration, cryogenic reaction facility, fractional distillation setup and warehouse support.
NMR, HPLC, LC-MS, GC-MS, UV/Vis, FT-IR, KF titration, potentiometry, polarimetry and stability chamber access on rental/GMP support basis.
Representative advanced intermediates, key starting materials and agrochemical intermediates. Additional compounds can be added or removed as required before website launch.
| S.No | CAS No. | Compound / Intermediate | Related API / Area |
|---|---|---|---|
| 1 | 1225383-63-0 | 4-[(2,6-Dichloro)-4-pyrimidinyloxy]-3,5-dimethylbenzonitrile | Etravirine |
| 2 | 955368-90-8 | 2-Allyl-6-(methylthio)-1,2-dihydro-3H-pyrazolo[3,4-d]pyrimidin-3-one | Adavosertib |
| 3 | 104641-60-3 | (R)-1-Methylpyrrolidin-3-ol | Larotrectinib |
| 4 | 1224944-77-7 | Ethyl 5-chloropyrazolo[1,5-a]pyrimidine-3-carboxylate | Repotrectinib |
| 5 | 536760-29-9 | 1-(4-Bromophenyl)piperidin-2-one | Apixaban |
| 6 | 93246-53-8 | 3-Fluoro-4-morpholinoaniline | Linezolid |
| 7 | 183322-18-1 | 4-Chloro-6,7-bis(2-methoxyethoxy)quinazoline | Erlotinib |
| 8 | 1408282-26-7 | 8-Fluoro-2,3,4,6-tetrahydro-1H-azepino[5,4,3-cd]indol-1-one | Rucaparib |
| 9 | 13790-39-1 | 4-Chloro-6,7-dimethoxyquinazoline | Fruquintinib |
| 10 | 503070-57-3 | 2-((2-((6-Bromohexyl)oxy)ethoxy)methyl)-1,3-dichlorobenzene | Vilanterol |
| 11 | 208925-08-0 | (R)-5-(2,2-Dimethyl-4H-benzo[d][1,3]dioxin-6-yl)oxazolidin-2-one | Vilanterol |
| 12 | 98977-36-7 | N-Boc-3-piperidone | Avarofloxacin / Gemigliptin |
| 13 | 87120-72-7 | 4-Amino-1-Boc-piperidine | Relebactam / Prucalopride |
| 14 | 22841-92-5 | 3-Chloro-2-hydrazinylpyridine | Chlorantraniliprole |
| 15 | 20776-67-4 | 2-Amino-5-chloro-3-methylbenzoic acid | Chlorantraniliprole |
| 16 | 28418-88-4 | 3-Iodophthalic anhydride | Flubendiamide |
| 17 | 111493-74-4 | Ethyl 1-methyl-3-(trifluoromethyl)-1H-pyrazole-4-carboxylate | Penthiopyrad |
| 18 | 85290-76-2 | Ethyl 1,3-dimethyl-1H-pyrazole-4-carboxylate | Penflufen |
| 19 | 5470-49-5 | 4-(Methylsulfonyl)aniline | Advanced intermediate |
| 20 | 761446-44-0 | 1-Methylpyrazole-4-boronic acid pinacol ester | Medicinal chemistry building block |
| 21 | 322-35-0 | Benserazide free base | API / reference standard |
| 22 | 31197-30-5 | 1-(3-Bromophenyl)piperazine | Piperazine building block |
| 23 | 79099-07-3 | 1-Boc-4-piperidone | Key starting material |
| 24 | 87-42-3 | 6-Chloropurine | Purine intermediate |
| 25 | 75-35-4 | 1,1-Dichloroethene | Specialty intermediate |
| 26 | 130922-39-3 | 2,3-Difluorobenzene-1-thiol | Fluorinated building block |
For project discussions, compound availability, samples and collaboration enquiries.
Sygmoid Chemical Sciences Pvt. Ltd.
397-B, FCI Road, Cherlapally, Hyderabad – 500051
drrajureddychem@gmail.com
rama@sygmoidchemicalsciences.com
madugularama3@gmail.com
Website: sygmoidchemicalsciences.com
+91 9985519940
+91 9441295329
Domain email: rama@sygmoidchemicalsciences.com